Sublingual Immunotherapy for Aeroallergens: Optimal Patient Dosing, Regimen and Duration
نویسندگان
چکیده
منابع مشابه
CSACI position statement: prescribing sublingual immunotherapy tablets for aeroallergens
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متن کاملSublingual immunotherapy for aeroallergens: status in the United States.
Sublingual immunotherapy (SLIT) has been used in the treatment of allergic disease for nearly 30 years and is prescribed at least as frequently as subcutaneous immunotherapy (SCIT). Several large U.S. clinical trials using single allergen tablets (grass and ragweed) or extract solution (ragweed) have met their primary clinical efficacy outcome. In December, 2013 the Federal Drug Administration ...
متن کاملMechanisms of immunotherapy to aeroallergens.
Allergen immunotherapy is allergen-specific, allergen dose- and time-dependent and is associated with long-term clinical and immunological tolerance that persists for years after discontinuation. Successful immunotherapy is accompanied by the suppression of numbers of T-helper 2 (Th2) effector cells, eosinophils, basophils, c-kit+mast cells and neutrophils infiltration in target organs, inducti...
متن کاملSublingual immunotherapy for allergic rhinitis and conjunctivitis.
Sublingual immunotherapy (SLIT) for allergic respiratory diseases was first described in 1986 and immediately appeared as a viable alternative to the traditional subcutaneous route. Since then, more than 60 randomized controlled trials have been published, almost all with very favorable results. The average improvement over placebo in symptom score and medication use was always greater than 20%...
متن کاملOral and sublingual immunotherapy for food allergy
OBJECTIVE Food allergies continue to be an increasingly common disorder, however, no treatment strategies are currently approved for the routine management of individuals with food allergies. Encouraging results from early open-label studies have sparked great interest in oral and sublingual immunotherapy, and thus several randomized controlled trials have recently been conducted to establish t...
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ژورنال
عنوان ژورنال: Current Treatment Options in Allergy
سال: 2014
ISSN: 2196-3053
DOI: 10.1007/s40521-013-0002-9